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Investigation of varicella-zoster virus-infected cell proteins that elicit antibody production during primary varicella using the immune transfer method (1984).
| Content Provider | CiteSeerX |
|---|---|
| Author | Palumbo, E. Arvin, Ann M. Ine, Cel Koropchak, M. Wittek, Andalec E. |
| Abstract | The varicella-zoster vi us-infected cell proteins (VZV-ICPs) against which IgG, IgM and IgA antibodies were made in the course of primary varicella-zoster virus (VZV) infection were analysed by the immune transfer method. IgG antibodies were made against one or more of 18 VZV-ICPs by patients with varicella. IgM antibodies were produced which reacted with 2I VZV-ICPs. The spectrum of IgG antibody production during the first week after the onset of infection was limited to an average of three VZV-ICPs while IgM antibodies which reacted with an average of seven VZV-ICPs were detectable in the acute phase of varicella. Equivalent VZV IgG or IgM antibody titres by radioimmunoassay did not correlate with a similar pattern of antibody specificity for VZV-ICPs by immune transfer. A detectable immune response to all VZV-ICPs was not required for the recovery of individual patients from primary VZV infection. |
| File Format | |
| Publisher Date | 1984-01-01 |
| Access Restriction | Open |
| Subject Keyword | Immune Transfer Method Primary Varicella Varicella-zoster Virus-infected Cell Elicit Antibody Production Igm Antibody Varicella-zoster Vi Us-infected Cell Protein Acute Phase Equivalent Vzv Igg Individual Patient Similar Pattern Igg Antibody Antibody Specificity Immune Transfer Primary Varicella-zoster Virus Primary Vzv Infection Igg Antibody Production First Week Igm Antibody Titre Iga Antibody Detectable Immune Response |
| Content Type | Text |