NDLI: Human temperature regulation during arterial hypercapnia induced by inhalanon of 4 % c02.

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Human temperature regulation during arterial hypercapnia induced by inhalanon of 4 % c02.

Content Provider	CiteSeerX
Author	Johnston, Chad E. White, Matthew D. Wu, Mingpu Elias, Dwayne A. Giesbrecht, Gordon G.
Abstract	Carbon dioxide concentrations may be elevated in diving operations. Hypercapnia may affect basic thermoregulatory responses and predispose divers to hypothermia. Early animal studies have shown that inhalation of gas mixtures containing 3 to 10 % CO2 during cold exposure impairs thermal homeostasis by attenuating shivering and promoting heat loss through peripheral vasodilation (Stupfel1974). The effects of hypercapnia in humans under similar conditions are less clear. Inhalation of 2.5 to 4 % CO2 mixtures have been reported to transiently suppress shivering without affecting core temperature (Tco) cooling rate (Bullard and Crise 1961, Lun et ai. 1994), to increase cooling rate without affecting shivering (Wagner et ai. 1983) or to have no significant effect on either shivering or core cooling (Lon et al. 1993). There are several limitations to previous work on the effects of hypercapnia on human thermoregulation. In addition to inconsistent results during cold stress, little is known about the thermoregulatory effects of hypercapnia during heat challenge. Also, the effects of hypercapnia on warm and cold response thresholds are unknown. Therefore, this study was performed to determine the effects of hypercapnia on core temperature thresholds for warm and cold thermoregulatory responses as well as the rate of core cooling during mild cold stress. METHODS
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Subject Keyword	Core Cooling Inconsistent Result Thermoregulatory Effect Co2 Mixture Peripheral Vasodilation Mild Cold Stress Heat Challenge Significant Effect Carbon Dioxide Concentration Core Temperature Previous Work Cold Stress Cold Thermoregulatory Response Early Animal Study Core Temperature Threshold Basic Thermoregulatory Response Predispose Diver Heat Loss Gas Mixture Several Limitation Cold Exposure Similar Condition Thermal Homeostasis Cold Response Threshold Human Thermoregulation
Content Type	Text

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