NDLI: Key words: ebv/lymphocytes/ebna can epstein-barr virus infect and transform all the b-lymphocytes of (1982).

Content Provider	CiteSeerX
Author	Zerbini, M. Ernberg, I.
Abstract	Quantitative aspects of Epstein-Barr virus infection and transformation f human neonatal B-lymphocytes have been investigated. 72 to 90 % B-cells were obtained with enrichment. Of the B-cells, 19 to 97 % showed nuclear antigen (EBNA) 2 days after infection. A difference between different B-cell donors in susceptibility to infection was noted. Analysis of the virus dose-response curves obtained with twofold virus dilutions howed that one virus particle is sufficient o induce EBNA in a cell. Of the infected cells, 50 to 95 % multiplied in microtitre wells containing a human fibroblast feeder layer, while only a small proportion established growing colonies in soft agarose, that could be picked up and subcultured.
File Format	PDF
Publisher Date	1982-01-01
Access Restriction	Open
Subject Keyword	Ebna Epstein-barr Virus Infect Key Word Quantitative Aspect Human Fibroblast Feeder Layer Virus Particle Virus Dose-response Curve Nuclear Antigen Infected Cell Transformation Human Neonatal B-lymphocytes Epstein-barr Virus Infection Twofold Virus Dilution Sufficient Induce Ebna Microtitre Well Soft Agarose Different B-cell Donor Small Proportion
Content Type	Text

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