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Biosensing with Luminescent Semiconductor Quantum Dots
| Content Provider | CiteSeerX |
|---|---|
| Author | Sapsford, Kim E. Pons, Thomas Medintz, Igor L. Mattoussi, Hedi |
| Abstract | Abstract: Luminescent semiconductor nanocrystals or quantum dots (QDs) are a recently developed class of nanomaterial whose unique photophysical properties are helping to create a new generation of robust fluorescent biosensors. QD properties of interest for biosensing include high quantum yields, broad absorption spectra coupled to narrow sizetunable photoluminescent emissions and exceptional resistance to both photobleaching and chemical degradation. In this review, we examine the progress in adapting QDs for several predominantly in vitro biosensing applications including use in immunoassays, as generalized probes, in nucleic acid detection and fluorescence resonance energy transfer (FRET)- based sensing. We also describe several important considerations when working with QDs mainly centered on the choice of material(s) and appropriate strategies for attaching biomolecules to the QDs. |
| File Format | |
| Journal | Sensors 2006 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Luminescent Semiconductor Quantum Dot Broad Absorption Spectrum New Generation Vitro Biosensing Application Appropriate Strategy Quantum Dot Robust Fluorescent Biosensors Fluorescence Resonance Energy Transfer Several Important Consideration Developed Class Exceptional Resistance Unique Photophysical Property Qd Property High Quantum Yield Sizetunable Photoluminescent Emission Chemical Degradation Luminescent Semiconductor Nanocrystals Nucleic Acid Detection |
| Content Type | Text |
| Resource Type | Article |
