NDLI: A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons (2000)

Content Provider	CiteSeerX
Author	Fitzli, Dora Stoeckli, Esther T. Kunz, Stefan Siribour, Kingsley Rader, Christoph Kunz, Beat Kozlov, Serguei V. Buchstaller, Rea Lane, Robert P. Suter, Daniel M. Eyer, William J. Sonderegger, Peter
Abstract	Abstract. An interaction of growth cone axonin-1 with the floor-plate NgCAM-related cell adhesion molecule (NrCAM) was shown to play a crucial role in commissural axon guidance across the midline of the spinal cord. We now provide evidence that axonin-1 mediates a guidance signal without promoting axon elongation. In an in vitro assay, commissural axons grew preferentially on stripes coated with a mixture of NrCAM and NgCAM. This preference was abolished in the presence of anti–axonin-1 antibodies without a decrease in neurite length. Consistent with these findings, commissural
File Format	PDF
Journal	KUNZ B, KOZLOV SV, BUCHSTALLER A, LANE RP, SUTER DM, DREYER WJ, AND SONDEREGGER
Language	English
Publisher Date	2000-01-01
Access Restriction	Open
Subject Keyword	Commissural Axon Direct Interaction Ngcam-related Cell Adhesion Molecule Axonin-1 Mediates Floor-plate Ngcam-related Cell Adhesion Molecule Growth Cone Axonin-1 Guidance Signal Axon Elongation Spinal Cord Vitro Assay Anti Axonin-1 Antibody Commissural Axon Guidance Neurite Length Crucial Role
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in