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Struct-NB: predicting protein-RNA binding sites using structural features (2010)
| Content Provider | CiteSeerX |
|---|---|
| Author | Towfic, Fadi Caragea, Cornelia Gemperline, David C. Dobbs, Ena Honavar, Vasant |
| Abstract | We analyse sequence and structural features of protein-RNA interfaces using RB-147, a non-redundant dataset of protein-RNA complexes extracted from the PDB. We train classifiers using machine learning algorithms to predict protein-RNA interfaces from sequence and structure-derived features of proteins. Our experiments show that Struct-NB, a Naive Bayes classifier that exploits structural features, outperforms its counterparts that use only sequence features to predict protein-RNA binding residues. |
| File Format | |
| Volume Number | 4 |
| Journal | INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS |
| Language | English |
| Publisher Date | 2010-01-01 |
| Access Restriction | Open |
| Subject Keyword | Structural Feature Protein-rna Binding Site Protein-rna Interface Non-redundant Dataset Structure-derived Feature Protein-rna Complex Naive Bayes Classifier Sequence Feature Protein-rna Binding Residue |
| Content Type | Text |
| Resource Type | Article |
