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| Content Provider | The American Society of Mechanical Engineers (ASME) Digital Collection |
|---|---|
| Author | Robert, V. Stigliano Shubitidze, Fridon Hoopes, P. Jack |
| Copyright Year | 2013 |
| Abstract | The use of magnetic nanoparticles (mNP’s) in hyperthermia therapy for the treatment of cancer has been receiving increasing interest in the past few decades. It is known that heating cancerous tissues to temperatures above physiologically normal levels will cause cytotoxicity. In mNP hyperthermia, mNP’s are either injected intravenously or directly into the tumor site. In many tumor types the nanoparticles are invaginated into the cancer cells and aggregated into endosomes. Local temperature increases are achievable by exposing tumors containing mNP’s to an alternating magnetic field (AMF). The proximity of the mNP’s has a strong influence on their ability to generate heat due to inter-particle magnetic interaction effects [1, 2]. Taking this effect into account is important when modeling the heating characteristics of mNP’s. |
| Sponsorship | Nanotechnology Institute Bioengineering Division |
| File Format | |
| ISBN | 9780791845332 |
| DOI | 10.1115/NEMB2013-93123 |
| Conference Proceedings | ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology |
| Language | English |
| Publisher Date | 2013-02-04 |
| Publisher Place | Boston, Massachusetts, USA |
| Access Restriction | Subscribed |
| Subject Keyword | Nanoparticles Patient treatment Temperature distribution Temperature Heat Heating Biological tissues Particulate matter Magnetic fields Modeling Cancer Tumors |
| Content Type | Text |
| Resource Type | Article |
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