NDLI: Microfabricated Thermal Gradient Separator Device

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Saputra, Null Geelhoed, P. F. Goosen, J. F. L. Lindken, R. Westerweel, J. Keulen, F. Van
Copyright Year	2009
Abstract	The design and fabrication of a microfabricated fluidic device for particle thermophoresis is presented. The ability of the device to concentrate particles by generating a huge thermal gradient is demonstrated. In contrast to other microfluidics devices which use electrokinetics or pressure driven flow, in this device no external force acts on the particles. The separator device has been fabricated in a standard silicon substrate, consisting of a 20 μm deep channel and a 600 nm thick aluminum heater integrated into the device. The device is able to create a thermal gradient of approximately 104 Km−1. To maintain a thermal gradient over a long period, special attention had to be given to the design of the integrated heater and thermal insulation of the channel. In order to deposit the aluminum heater on the side wall of a micro channel, a silicon substrate was wet etched in KOH solution, forming sloping sidewalls. The temperature difference was measured using a thermocouple mounted on the two sides of the channel walls, showing about 2 K temperature difference. Experimental studies have been conducted in order to study the motion of particles in response to the thermal gradient. Particle motions are recorded before and after turning on the heater. Using polystyrene latex particles suspended in de-ionized water, it is shown that 90% of particles are concentrated on the cold side of the channel after 300 seconds using only 1W of electrical power. Apart from its applicability to particle suspensions, this device also has a great potential for DNA molecule concentration and separation in bio-chemical analysis.
Sponsorship	Nanotechnology Institute
Starting Page	379
Ending Page	386
Page Count	8
File Format	PDF
ISBN	9780791843895
DOI	10.1115/MNHMT2009-18543
e-ISBN	9780791838648
Volume Number	ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer, Volume 1
Conference Proceedings	ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer
Language	English
Publisher Date	2009-12-18
Publisher Place	Shanghai, China
Access Restriction	Subscribed
Subject Keyword	Separation Thermophoresis Microfluidics Thermal gradient Separation (technology) Temperature gradient
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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