NDLI: Method for Individual Control of Multiplexed Droplet Generation in Digital Microfluidic Devices

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Michael, J. Schertzer Yang, Zhifang Ben-Mrad, Ridha Pierre, E. Sullivan
Copyright Year	2013
Abstract	This investigation presents two methods for multiplexed droplet generation in digital microfluidic devices. Analytical and experimental results show that the number of electrical output signals required for multiple reagent systems can be reduced by electrically connecting all but one electrode in each droplet generation path on the device. Both methods reduce the number of electrical signals required for generating droplets from multiple reservoirs by M(N−1), where M is the number of manipulation electrodes in the generation path and N is the number of reservoirs on the device. The first method uses individually controlled reservoirs to minimize the manipulation of the fluid in the unused reservoir, while the second method individually controls one of the electrodes in the generation pathway to allow for closed loop control of droplet generation. In both cases, droplets are kept at rest by simultaneously activating or deactivating all adjacent electrodes. These methods can be easily integrated into devices with multiple reservoirs without computational expense or prior knowledge of the electrode activation sequence. They can also be used in concert with droplet control algorithms for pin constrained systems to further reduce the number of output channels required in a digital microfluidic device.
File Format	PDF
ISBN	9780791856321
DOI	10.1115/IMECE2013-65935
Volume Number	Volume 7B: Fluids Engineering Systems and Technologies
Conference Proceedings	ASME 2013 International Mechanical Engineering Congress and Exposition
Language	English
Publisher Date	2013-11-15
Publisher Place	San Diego, California, USA
Access Restriction	Subscribed
Subject Keyword	Electrodes Fluids Drops Control algorithms Reservoirs Signals Microfluidics
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in