NDLI: Tunable Morphology of Monodisperse Polymer Particles With Microfluidics

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Wang, Baoguo David, A. Weitz Shum, Ho Cheung
Copyright Year	2011
Abstract	In this work, we propose a novel method to fabricate polymer particles with controlled morphology in microchannel by solidification of polymer solutions and study the transition in the shape of these particles from spheres, to cups, and to donuts. The non-spherical geometries are achieved through nonuniform diffusion of the solvent, leading to non-uniform solidification. By adjusting the flow rates of both continuous and dispersed phases, the spatial heterogeneity in the solvent diffusion rate and thus the morphology of the final polymer particles can be tuned. This approach offers a one-step continuous process for the fabrication of non-spherical polymer particles. The technique is applicable to different polymers under appropriate polymer-solvent combinations. The ability to tune the shapes of polymer particles easily will create new opportunities for applications that require anisotropic functional particles, such as in biomedical engineering.
Sponsorship	Heat Transfer Division
Starting Page	29
Ending Page	34
Page Count	6
File Format	PDF
ISBN	9780791844649
DOI	10.1115/ICNMM2011-58119
Volume Number	ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels, Volume 2
Conference Proceedings	ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels
Language	English
Publisher Date	2011-06-19
Publisher Place	Edmonton, Alberta, Canada
Access Restriction	Subscribed
Subject Keyword	Polymer solutions Anisotropy Particulate matter Shapes Manufacturing Polymers Diffusion (physics) Flow (dynamics) Microfluidics Solidification Biomedical engineering Microchannels
Content Type	Text
Resource Type	Article

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