NDLI: A New Circulation Model Combined With a Detailed Network Model of Arterial Blood Flow

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Kim, Y. T. Kwon, S. S. Kim, E. B.
Copyright Year	2011
Abstract	This study developed a model of the entire cardiovascular system combined with a Laplace heart based on the numerical cardiac-cell model and a detailed arterial-network structure. Our model incorporates the Laplace heart model and pulmonary model using a lumped-parameter model with a distributed arterial-system model. The Laplace heart acts as a pump and consists of an atrium and ventricle. We applied a cellular-contraction model modulated by the calcium concentration and action potential in a single cell. The numerical arterial model is based on a numerical solution of the one-dimensional momentum equations and the continuity equation of flow and vessel wall motion in a geometrically accurate branching network of the arterial system that includes energy loss at bifurcations. To validate our method, the computed pressure waves were compared with existing experimental observations. Using the combined cell–system–arterial network model, pathophysiological events at levels from cells to the arterial network are delineated.
Sponsorship	Fluids Engineering Division
Starting Page	2019
Ending Page	2021
Page Count	3
File Format	PDF
ISBN	9780791844403
DOI	10.1115/AJK2011-19006
Volume Number	ASME-JSME-KSME 2011 Joint Fluids Engineering Conference: Volume 1, Symposia – Parts A, B, C, and D
Conference Proceedings	ASME-JSME-KSME 2011 Joint Fluids Engineering Conference
Language	English
Publisher Date	2011-07-24
Publisher Place	Hamamatsu, Japan
Access Restriction	Subscribed
Subject Keyword	Cardiovascular system Energy dissipation Pumps Vessels Bifurcation Network models Momentum Flow (dynamics) Pressure Waves Blood flow
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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