NDLI: Multiple fault diagnosis in digital microfluidic biochips

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Multiple fault diagnosis in digital microfluidic biochips

Content Provider	ACM Digital Library
Author	Davids, Daniel Datta, Siddhartha Mukherjee, Arindam Joshi, Bharat Ravindran, Arun
Copyright Year	2006
Abstract	Microfluidics-based biochips consist of microfluidic arrays on rigid substrates through which, movement of fluids is tightly controlled to facilitate biological reactions. Biochips are soon expected to revolutionize biosensing, clinical diagnostics, and drug discovery. Critical to the deployment of biochips in such diverse areas is the dependability of these systems. Thus, robust testing techniques are required to ensure an adequate level of system dependability. Due to the underlying mixed technology and energy domains, such biochips exhibit unique failure mechanisms and defects. In this article we present a highly effective fault diagnosis strategy that uses a single source and sink to detect and locate multiple faults in a microfluidic array, without flooding the array, a problem that has hampered realistic implementations of all existing strategies. The strategy renders itself well for a built-in self-test that could drastically reduce the operating cost of microfluidic biochips. It can be used during both the manufacturing phase of the biochip, as well as field operation. Furthermore, the algorithm can pinpoint the actual fault, as opposed to merely the faulty regions that are typically identified by strategies proposed in the literature. Also, analytical results suggest that it is an effective strategy that can be used to design highly dependable biochip systems.
Starting Page	262
Ending Page	276
Page Count	15
File Format	PDF
ISSN	15504832
e-ISSN	15504840
DOI	10.1145/1216396.1216398
Journal	ACM Journal on Emerging Technologies in Computing Systems (JETC)
Volume Number	2
Issue Number	4
Language	English
Publisher	Association for Computing Machinery (ACM)
Publisher Date	2006-10-01
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Microfluidic biochip Droplet flooding Faults tolerance Multiple fault Testing
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering Hardware and Architecture Nanoscience and Nanotechnology Software

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