NDLI: Pacemaker control of heart rate variability: A cyber physical system perspective

Content Provider	ACM Digital Library
Author	Marculescu, Radu Bogdan, Paul Jain, Siddharth
Copyright Year	2013
Abstract	Cardiac diseases, like those related to abnormal heart rate activity, have an enormous economic and psychological impact worldwide. The approaches used to control the behavior of modern pacemakers ignore the fractal nature of heart rate activity. The purpose of this article is to present a Cyber Physical System approach to pacemaker design that exploits precisely the fractal properties of heart rate activity in order to design the pacemaker controller. Towards this end, we solve a finite horizon optimal control problem based on the heartbeat time series and show that this control problem can be converted into a system of linear equations. We also compare and contrast the performance of the fractal optimal control problem under six different cost functions. Finally, to get an idea of hardware complexity, we implement the fractal optimal controller on a Virtex4 FPGA and report some preliminary results in terms of area overhead.
Starting Page	1
Ending Page	22
Page Count	22
File Format	PDF
ISSN	15399087
e-ISSN	15583465
DOI	10.1145/2435227.2435246
Volume Number	12
Issue Number	1s
Journal	ACM Transactions on Embedded Computing Systems (TECS)
Language	English
Publisher	Association for Computing Machinery (ACM)
Publisher Date	2013-03-21
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Cyber physical systems Fractal behavior Fractional calculus Heart rate variability Non-stationary behavior Optimal control
Content Type	Text
Resource Type	Article
Subject	Hardware and Architecture Software

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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