NDLI: Quantitative measurement of split of the second heart sound (S2)

Content Provider	ACM Digital Library
Author	Chen, Bo-Wei Barma, Shovan Man, Ka Lok Wang, Jhing-Fa
Copyright Year	2015
Description	Author Affiliation: National Cheng Kung University, and Tajen University, Taiwan(Chen, Bo-Wei; National cheng kung university, Tainan, Taiwan (ROC) (Barma, Shovan; Xi'an jiaotong-liverpool university, China (Man, Ka Lok); Roc) (wang, Jhing-Fa))
Abstract	This study proposes a quantitative measurement of split of the second heart sound (S2) based on nonstationary signal decomposition to deal with overlaps and energy modeling of the subcomponents of S2. The second heart sound includes aortic (A2) and pulmonic (P2) closure sounds. However, the split detection is obscured due to A2-P2 overlap and low energy of P2. To identify such split, HVD method is used to decompose the S2 into a number of components while preserving the phase information. Further, A2s and P2s are localized using smoothed pseudo Wigner-Ville distribution followed by reassignment method. Finally, the split is calculated by taking the differences between the means of time indices of A2s and P2s. Experiments on total 33 clips of S2 signals are performed for evaluation of the method. The mean ± standard deviation of the split is 34.7 ± 4.6 ms. The method measures the split efficiently, even when A2-P2 overlap is ≤ 20 ms and the normalized peak temporal ratio of P2 to A2 is low (≥ 0.22). This proposed method thus, demonstrates its robustness by defining split detectability (SDT), the split detection aptness through detecting P2s, by measuring upto 96 percent. Such findings reveal the effectiveness of the method as competent against the other baselines, especially for A2-P2 overlaps and low energy P2.
Starting Page	851
Ending Page	860
Page Count	10
File Format	PDF
ISSN	15455963
DOI	10.1109/TCBB.2014.2351804
Volume Number	12
Issue Number	4
Journal	IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Language	English
Publisher	Association for Computing Machinery (ACM)
Publisher Date	2015-07-01
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	A2 and P2 Empirical mode decomposition (EMD) Hilbert vibration decomposition (HVD) Second heart sound (S2) Split
Content Type	Text
Resource Type	Article
Subject	Genetics Biotechnology Applied Mathematics

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