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Techniques for Scanned Illumination
| Content Provider | The Lens |
|---|---|
| Abstract | Imaging systems are provided for high speed, high resolution imaging of biochemical materials. In an example embodiment, an imaging system comprises an objective lens component, a line generator, a digital camera, a positioning stage, and a scan mirror. The line generator generates a line of light that is scanned across a portion of a substrate that is mounted on the positioning stage. The positioning stage moves the substrate in a particular direction that is substantially normal to an optical axis of the objective lens component. The camera collects an image of the portion of the substrate through the objective lens component. The scan mirror moves in coordination with the positioning stage, while the line of light is being scanned across the portion of the substrate and the substrate is being moved in the particular direction, in order to keep the image still with respect to the camera while the image is being collected by the camera. |
| Related Links | https://www.lens.org/lens/patent/106-772-070-827-024/frontpage |
| Language | English |
| Publisher Date | 2017-01-12 |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Patent |
| Jurisdiction | United States of America |
| Date Applied | 2016-09-23 |
| Applicant | Complete Genomics Inc |
| Application No. | 201615274936 |
| Claim | - 25 . (canceled) A method of operating a digital camera comprising steps of: (a) scanning a thin strip of light across an object to expose row by row pixels in an image sensor of the digital camera; and (b) reading out the pixels row by row in rolling readout mode after exposure in step (a). The method of claim 26 , wherein reading out the pixels takes longer than scanning the thin strip of light across the object. The method of claim 27 , wherein the pixels are kept dark between exposure and reading out. The method of claim 26 , wherein the camera comprises a split-readout sensor having at least two sections, and wherein steps (a) and (b) are performed independently in each section of the sensor. The method of claim 26 , wherein steps (a) and (b) in one section are performed in parallel to steps (a) and (b) in another section. The method of claim 26 , wherein steps (a) and (b) in one section are performed in anti-parallel to steps (a) and (b) in another section. The method of claim 26 , wherein the camera is operating in correlated double sampling mode. The method of claim 26 , wherein the thin strip of light has a wavelength appropriate for fluorescence excitation while pixels in the image sensor are exposed by light having a wavelength corresponding to fluorescence emission. The method of claim 26 , wherein the thin strip of light exposes two or more rows of pixels at a time. The method of claim 26 wherein step (a) comprises: scanning a line of light by changing an angle of a scan mirror so that the image of the portion of the object that is acquired by an objective lens component is kept still with respect to the digital camera while the object is moving in a continuous motion, thereby exposing first one or more rows of pixels spanned by the image while keeping in the dark a second one or more rows of pixels spanned by the image; and wherein step (b) comprises reading out the first one or more rows of pixels while continuing to scan the line of light across the portion of the object thereby exposing the second one or more rows of pixels. The method of claim 35 wherein a third one or more rows of pixels are different than the first one or more rows of pixels. |
| CPC Classification | Investigating Or Analysing Materials By Determining Their Chemical Or Physical Properties OPTICAL ELEMENTS; SYSTEMS OR APPARATUS IMAGE DATA PROCESSING OR GENERATION; IN GENERAL PICTORIAL COMMUNICATION; e.g. TELEVISION |
| Extended Family | 015-024-383-036-933 189-799-366-297-57X 174-357-489-102-178 106-772-070-827-024 026-110-924-606-004 147-914-489-297-614 183-411-277-705-824 102-033-300-895-491 171-076-044-387-043 167-391-455-583-001 032-144-611-569-508 197-907-996-039-028 174-332-014-218-803 051-069-711-225-464 085-010-086-025-738 044-318-619-511-047 189-391-695-802-195 125-003-229-592-099 092-836-709-902-050 161-172-245-053-135 193-650-615-371-953 110-064-039-416-566 049-943-677-648-303 120-717-883-958-203 129-383-615-753-973 |
| Patent ID | 20170013220 |
| Inventor/Author | Staker Bryan P Uhrich Craig E |
| IPC | H04N5/374 G06T1/00 H04N3/08 H04N5/225 H04N5/345 H04N5/378 |
| Status | Discontinued |
| Simple Family | 015-024-383-036-933 085-010-086-025-738 044-318-619-511-047 189-799-366-297-57X 106-772-070-827-024 125-003-229-592-099 183-411-277-705-824 092-836-709-902-050 193-650-615-371-953 032-144-611-569-508 110-064-039-416-566 120-717-883-958-203 129-383-615-753-973 |
| CPC (with Group) | G01N21/6456 G02B21/365 G06T1/0007 G06T2207/30072 G06T2207/10056 G01N21/6452 H04N25/78 H04N3/08 H04N23/56 H04N25/441 H04N25/531 H04N25/767 G02B21/361 H04N7/18 G06T2207/10064 G06T2207/10152 G06T2207/30004 |
| Issuing Authority | United States Patent and Trademark Office (USPTO) |
| Kind | Patent Application Publication |
