Hydrodissection and Posterior Capsule Opacification Prevention During Capsulotomy Procedure

Content Provider	The Lens
Abstract	Embodiments of the invention provide hydrodissection and/or PCO prevention or reduction in a patient undergoing eye surgery. In one embodiment, the invention is a surgical device for cutting and excising a portion of tissue, for example in performing a lens capsulotomy. A capsulotomy tip is inserted into an eye through an incision in the surface of the eye. The capsulotomy tip includes a suction cup to provide suction to the lens capsule. Then suction is applied via the suction cup to secure the capsulotomy tip to the eye. In some embodiments, after the capsulotomy tip is secured to the lens capsule, a cutting element of the capsulotomy tip is used to cut a tissue of the eye. Fluid is pushed through the capsulotomy tip and the capsulotomy tip is removed from the eye. Moreover, disclosed is an intraocular lens (IOL) to be used in conjunction with the surgical device.
Related Links	https://www.lens.org/lens/patent/009-527-843-530-148/frontpage
Language	English
Publisher Date	2019-08-01
Access Restriction	Open
Content Type	Text
Resource Type	Patent
Jurisdiction	United States of America
Date Applied	2019-01-25
Applicant	Mynosys Cellular Devices Inc
Application No.	201916257477
Claim	A method for performing a capsulotomy, comprising: inserting a capsulotomy tip of a capsulotomy device into an eye of a patient through an incision in a surface of the eye; applying suction to the capsulotomy tip to secure the capsulotomy tip to the eye of the patient; cutting tissue of the eye of the patient, such that an edge of the cut tissue rolls to form a converging fluidic inlet under the edge; pushing a fluid through the capsulotomy tip; and removing the capsulotomy tip from the eye of the patient. The method of claim 1 , further comprising: prior to inserting the capsulotomy tip into the eye of the patient, filling the capsulotomy tip and a suction tube of the capsulotomy device with the fluid. The method of claim 1 , wherein the fluid comprises one of a balanced salt solution (BSS), a viscoelastic fluid, and sterile water. The method of claim 1 , wherein a volume of fluid pushed through the capsulotomy tip is between 0.02 ml and 1.0 m The method of claim 1 , wherein the fluid is pushed through the capsulotomy tip between the inner surface of the lens capsule and outer surface of the lens of the eye through the cut in the tissue of the eye of the patient. The method of claim 5 , wherein the fluid hydrodissects a capsule away from the lens of the eye. The method of claim 5 , wherein the fluid kills lens epithelial cells in the capsule of the eye. The method of claim 5 , wherein the fluid detaches lens epithelial cells from the capsule of the eye. The method of claim 1 , wherein the fluid is delivered by advancing a roller in a roller dispenser that mechanically forces fluid to flow into the suction cup of the capsulotomy device. The method of claim 1 , wherein the suction is applied to the capsulotomy tip by operating a peristaltic pump in a first direction, and wherein the fluid is pushed through the capsulotomy tip by operating the peristaltic pump in a second direction, opposite from the first direction. The method of claim 1 , wherein the capsulotomy tip comprises a circular suction cup, and wherein the fluid is dispensed through the entire circumference of the circular suction cup. The method of claim 11 , wherein the capsulotomy tip further comprises a circular cutting element for cutting the tissue of the eye of the patient, the circular cutting element having a diameter smaller than a diameter of the suction cup. The method of claim 1 , wherein cutting tissue of the eye of the patient comprises: cutting tissue of the eye such that an edge of the cut tissue rolls to form a converging fluidic inlet under the rolled edge. The method of claim 1 , wherein cutting tissue of the eye of the patient comprises: cutting tissue of the eye using a heating element, wherein the heating element causes a shrinkage of collagen fibers resulting in an upward fold of the cut tissue. The method of claim 1 , further comprising: removing the cut tissue from the eye of the patient; inserting an intraocular lens into a capsular bag space of the eye of the patient; and fixating the intraocular lens in place utilizing an intraocular feature that provides for location or registration or physical interaction with the capsulotomy edge. The method of claim 15 , where the intraocular feature that provide for location, registration or physical interaction with tissue areas are adjacent to the capsulotomy edge. A surgical device comprising: a suction cup; a stem coupled to the suction cup, the stem including a lumen that is in fluid communication with the suction cup; an electrical cutting element for cutting tissue, wherein the electrical cutting element is mounted on an underside of the suction cup, the electrical cutting element configured to cause a shrinkage of collagen fibers resulting in an upward fold of the cut tissue; and a roller dispenser coupled to the lumen of the stem, the roller dispenser configured to dispense a predetermined amount of fluid through the lumen to the suction cup. The surgical device of claim 17 , wherein the electrical cutting element includes an electrical lead, the electrical lead configured to send an electrical pulse to the electrical cutting element. The surgical device of claim 17 , wherein the suction cup comprises: an inner diameter wall, an outer diameter wall, and a roof, the inner diameter wall, the outer diameter wall, and the roof forming a channel, the lumen of the stem coupled to the channel, and a lip coupled to the outer diameter wall, the lip configured to be pulled against a capsular membrane of an eye to form a low leakage seal to allow a pressure inside the channel to decrease. The surgical device of claim 19 , wherein the suction cup is circular in shape, and wherein the channel formed by the inner wall, the outer wall, and the roof has a ring shape. The surgical device of claim 17 , wherein the suction cup comprises: an inner membrane coupled to the inner diameter wall, and a plurality of standoffs on the inner membrane. The surgical device of claim 17 , wherein the suction cup comprises: a baffle disposed near the stem, the baffle for equalizing a flow rate around the suction cup. The surgical device of claim 17 , wherein the roller dispenser comprises: a housing including a bottom surface and a side surface, a track disposed on the side surface of the housing; a roller configured to move along the track of the housing; a compliant surface disposed on the bottom surface of the housing; and a tube disposed between the roller and the compliant surface, the tube of the roller dispenser in fluid communication with the lumen of the stem, wherein the tube is configured to allow fluid to flow through the roller dispenser when the roller is at a first end of the track, wherein the roller is configured to clamp the tube as the roller is advanced along the track, and wherein after the tube is clamped by the roller, the roller is configured to push a fluid disposed inside the tube as the roller is further advanced along the track towards a second end of the track. The surgical device of claim 24 , wherein the compliant surface is composed of a foam material to allow the roller to be advanced along the track up to the second end of the track after the roller has clamped the tube. The surgical device of claim 23 , wherein the compliant surface is composed of a soft material that allows the compliant surface to be compressed by a force exerted when the roller is clamping the tube. The surgical device of claim 17 , wherein the roller dispenser is configured to dispense a volume of fluid between 0.02 ml and 1.0 m The surgical device of claim 17 , wherein the fluid hydrodissects a capsule away from a lens of an eye of a patient. The surgical device of claim 17 , wherein the dispenser comprises: a housing including a bottom surface, a side surface, and a track disposed on the side surface of the housing; a roller configured to move along the track of the housing; a tube disposed between the roller and the bottom surface, the tube in fluid communication with the lumen of the stem, wherein the tube is configured to allow fluid to flow through the dispenser when the roller is at a first end of the track, wherein the roller is configured to pinch the tube shut as the roller is advanced along the track, and wherein after the tube is clamped by the roller, the roller is configured to push a fluid disposed inside the tube as the roller is further advanced along the track towards a second end of the track; and wherein the track comprises a first portion to guide the roller for pinching the tube closed, and a second portion that runs parallel to the bottom surface of the housing. A package comprising the surgical device of claim 17 and an intraocular lens having only rounded edges. A method for performing a capsulotomy, comprising: inserting a capsulotomy tip of a capsulotomy device into an eye of a patient through an incision in a surface of the eye; applying suction to the capsulotomy tip to secure the capsulotomy tip to the eye of the patient; cutting tissue of the eye of the patient using an electrical cutting element of the capsulotomy device, wherein the electrical cutting element causes a shrinkage of collagen fibers resulting in an upward fold of the cut tissue; pushing a fluid through the capsulotomy tip; and removing the capsulotomy tip from the eye of the patient. The method of claim 30 , further comprising: prior to inserting the capsulotomy tip into the eye of the patient, filling the capsulotomy tip and a suction tube of the capsulotomy device with the fluid. The method of claim 30 , wherein the fluid comprises one of a balanced salt solution (BSS), a viscoelastic fluid, and sterile water. The method of claim 30 , wherein a volume of fluid pushed through the capsulotomy tip is between 0.02 ml and 1.0 m The method of claim 30 , wherein the fluid is pushed through the capsulotomy tip between the inner surface of the lens capsule and outer surface of the lens of the eye through the cut in the tissue of the eye of the patient. The method of claim 30 , wherein the fluid hydrodissects a capsule away from the lens of the eye. The method of claim 30 , wherein the fluid kills lens epithelial cells in the capsule of the eye. The method of claim 30 , wherein the fluid detaches lens epithelial cells from the capsule of the eye. The method of claim 30 , wherein the fluid is delivered by advancing a roller in a roller dispenser that mechanically forces fluid to flow into the suction cup of the capsulotomy device. The method of claim 30 , wherein the suction is applied to the capsulotomy tip by operating a peristaltic pump in a first direction, and wherein the fluid is pushed through the capsulotomy tip by operating the peristaltic pump in a second direction, opposite from the first direction. The method of claim 30 , wherein the capsulotomy tip comprises a circular suction cup, and wherein the fluid is dispensed through the entire circumference of the circular suction cup. The method of claim 30 , wherein the capsulotomy tip further comprises a circular cutting element for cutting the tissue of the eye of the patient, the circular cutting element having a diameter smaller than a diameter of the suction cup. The method of claim 30 , wherein cutting tissue of the eye of the patient comprises: cutting tissue of the eye such that an edge of the cut tissue rolls to form a converging fluidic inlet under the rolled edge. The method of claim 30 , further comprising: removing the cut tissue from the eye of the patient; inserting an intraocular lens into a capsular bag space of the eye of the patient; and fixating the intraocular lens in place utilizing an intraocular feature that provides for location or registration or physical interaction with the capsulotomy edge. The method of claim 30 , wherein cutting the tissue of the eye of the patient further comprises: generating an electrical pulse through the electrical cutting element, the electrical pulse lasting less than 10 ms.
CPC Classification	Filters Implantable Into Blood Vessels; Prostheses; Devices Providing Patency To; Or Preventing Collapsing Of; Tubular Structures Of The Body; E.G. Stents; Orthopaedic; Nursing Or Contraceptive Devices; Fomentation; Treatment Or Protection Of Eyes Or Ears; Bandages; Dressings Or Absorbent Pads; First-Aid Kits Diagnosis; Surgery; Identification Devices For Introducing Media Into; Or Onto; The Body ;Devices For Transducing Body Media Or For Taking Media From The Body ;Devices For Producing Or Ending Sleep Or Stupor
Extended Family	142-945-480-208-371 192-329-662-678-125 009-527-843-530-148 085-019-091-189-930 111-103-941-780-704 126-869-203-302-579
Patent ID	20190231593
Inventor/Author	Keller Christopher Guild Mcgaffigan Thomas Haynes Waltz Kevin L Mcnicholas Thomas Milton
IPC	A61F9/007 A61B18/08 A61F2/16 A61F9/008 A61M1/00
Status	Active
Owner	Centricity Vision Inc
Simple Family	142-945-480-208-371 192-329-662-678-125 009-527-843-530-148 085-019-091-189-930 111-103-941-780-704 126-869-203-302-579
CPC (with Group)	A61F9/00754 A61F2009/00889 A61B18/08 A61B2018/00291 A61B2018/00601 A61B2018/00321 A61M1/77 A61F9/008 A61F2/16
Issuing Authority	United States Patent and Trademark Office (USPTO)
Kind	Patent Application Publication